Nonlinear mechanics with photonic crystal nanomembranes

Optomechanical systems close to their quantum ground state and nonlinear nanoelectromechanical systems are two hot topics of current physics research. As high-reflectivity and low mass are crucial features to improve optomechanical coupling towards the ground state, we have designed, fabricated and characterized photonic crystal nanomembranes, at the crossroad of both topics. Here we demonstrate a number of nonlinear effects with these membranes. We first characterize the nonlinear behavior of a single mechanical mode and we demonstrate its nonlocal character by monitoring the subsequent actuation-related frequency shift of a different mode. We then proceed to study the underlying nonlinear dynamics, both by monitoring the phase-space trajectory of the free resonator and by characterizing the mechanical response in presence of a strong pump excitation. We observe in particular the frequency evolution during a ring-down oscillation decay, and the emergence of a phase conjugate mechanical response to a weaker probe actuation. Our results are crucial to understand the full nonlinear features of the PhC membranes, and possibly to look for nonlinear signatures of the quantum dynamics

A micropillar for cavity optomechanics

We present a new micromechanical resonator designed for cavity optomechanics. We have used a micropillar geometry to obtain a high-frequency mechanical resonance with a low effective mass and a very high quality factor. We have coated a 60-$\mu$m diameter low-loss dielectric mirror on top of the pillar and are planning to use this micromirror as part of a high-finesse Fabry-Perot cavity, to laser cool the resonator down to its quantum ground state and to monitor its quantum position fluctuations by quantum-limited optical interferometry

Memory in autism spectrum disorder: a meta-analysis of experimental studies

To address inconsistencies in the literature on memory in Autism Spectrum Disorder (ASD), we report the first ever meta-analysis of short-term (STM) and episodic long-term (LTM) memory in ASD, evaluating the effects of type of material, type of retrieval and the role of inter-item relations. Analysis of 64 studies comparing individuals with ASD and typical development (TD) showed greater difficulties in ASD compared to TD individuals in STM (Hedges’ g=-0.53 [95%CI -0.90; -0.16], p=.005, I²=96%) compared to LTM (g=-0.30 [95%CI -0.42; -0.17], p<.00001, I²=24%), a small difficulty in verbal LTM (g=-0.21, p=.01), contrasting with a medium difficulty for visual LTM (g= -0.41, p=.0002) in ASD compared to TD individuals. We also found a general diminution in free recall compared to cued recall and recognition (LTM, free recall: g=-0.38, p<.00001, cued recall: g=-0.08, p=.58, recognition: g=-0.15, p=.16; STM, free recall: g=-0.59, p=.004, recognition: g=-0.33, p=.07). We discuss these results in terms of their relation to semantic memory. The limited diminution in verbal LTM and preserved overall recognition and cued recall (supported retrieval) may result from a greater overlap of these tasks with semantic long-term representations which are overall preserved in ASD. By contrast, difficulties in STM or free recall may result from less overlap with the semantic system or may involve additional cognitive operations and executive demands. These findings highlight the need to support STM functioning in ASD and acknowledge the potential benefit of using verbal materials at encoding and broader forms of memory support at retrieval to enhance performance

Breakdown of Scaling in the Nonequilibrium Critical Dynamics of the Two-Dimensional XY Model

The approach to equilibrium, from a nonequilibrium initial state, in a system at its critical point is usually described by a scaling theory with a single growing length scale, $\xi(t) \sim t^{1/z}$, where z is the dynamic exponent that governs the equilibrium dynamics. We show that, for the 2D XY model, the rate of approach to equilibrium depends on the initial condition. In particular, $\xi(t) \sim t^{1/2}$ if no free vortices are present in the initial state, while $\xi(t) \sim (t/\ln t)^{1/2}$ if free vortices are present.Comment: 4 pages, 3 figure

The Impact of Electrical Stimulation and Exercise on Independent Static Standing Balance

Purpose: Maintaining balance requires a complex integration of input from multiple sensory systems. Studies have shown positive effects of using transcutaneous electrical stimulation (TENS) and neuromuscular electrical stimulation (NMES) to enhance somatosensory feedback and muscular strength associated with balance. The purpose of this study is to examine the effects of electrical stimulation on independent standing balance during single leg stance (SLS) using either NMES with exercise, TENS with exercise, or exercise alone. Subjects: Fourteen subjects were recruited through a convenience sample on the University of Puget Sound campus. Methods: Randomized control trial. Subjects participated in this study five times per week for a total of six weeks. Participants were randomly assigned into each group: NMES with home exercise program (HEP),TENS with HEP and HEP-only. The experimental groups performed 60 minutes of electrical stimulation. All groups received the same HEP. SLS balance assessment was performed on each participant at one and six weeks. Results: Change in SLS over time showed no significant difference (p=0.67; power=0.10). There was no significant difference between groups (p=0.96; power=0.05). There was a significant difference in SLS time between eyes open versus eyes closed (p Conclusions: There was no significant difference in SLS time with the use of NMES, TENS or exercise alone. Relevance: This study suggests that applying electrical stimulation with described protocols may not have an effect on independent static standing balance. Further research should be done that incorporates other protocols and parameters

2D photonic-crystal optomechanical nanoresonator

We present the optical optimization of an optomechanical device based on a suspended InP membrane patterned with a 2D near-wavelength grating (NWG) based on a 2D photonic-crystal geometry. We first identify by numerical simulation a set of geometrical parameters providing a reflectivity higher than 99.8 % over a 50-nm span. We then study the limitations induced by the finite value of the optical waist and lateral size of the NWG pattern using different numerical approaches. The NWG grating, pierced in a suspended InP 265 nm-thick membrane, is used to form a compact microcavity involving the suspended nano-membrane as end mirror. The resulting cavity has a waist size smaller than 10 $\mu$m and a finesse in the 200 range. It is used to probe the Brownian motion of the mechanical modes of the nanomembrane

Quantifying the Energetics and Length Scales of Carbon Segregation to Fe Symmetric Tilt Grain Boundaries Using Atomistic Simulations

Segregation of impurities to grain boundaries plays an important role in both the stability and macroscopic behavior of polycrystalline materials. The research objective in this work is to better characterize the energetics and length scales involved with the process of solute and impurity segregation to grain boundaries. Molecular dynamics simulations are used to calculate the segregation energies for carbon within multiple grain boundary sites over a database of 125 symmetric tilt grain boundaries in Fe. The simulation results show that the majority of atomic sites near the grain boundary have segregation energies lower than in the bulk. Moreover, depending on the boundary, the segregation energies approach the bulk value approximately 5-12 \AA\ away from the center of the grain boundary, providing an energetic length scale for carbon segregation. A subsequent data reduction and statistical representation of this dataset provides critical information such as about the mean segregation energy and the associated energy distributions for carbon atoms as a function of distance from the grain boundary, which quantitatively informs higher scale models with energetics and length scales necessary for capturing the segregation behavior of impurities in Fe. The significance of this research is the development of a methodology capable of ascertaining segregation energies over a wide range of grain boundary character (typical of that observed in polycrystalline materials), which herein has been applied to carbon segregation in a specific class of grain boundaries in iron

Growth saturation of unstable thin films on transverse-striped hydrophilic-hydrophobic micropatterns

Using three-dimensional numerical simulations, we demonstrate the growth saturation of an unstable thin liquid film on micropatterned hydrophilic-hydrophobic substrates. We consider different transverse-striped micropatterns, characterized by the total fraction of hydrophilic coverage and the width of the hydrophilic stripes. We compare the growth of the film on the micropatterns to the steady states observed on homogeneous substrates, which correspond to a saturated sawtooth and growing finger configurations for hydrophilic and hydrophobic substrates, respectively. The proposed micropatterns trigger an alternating fingering-spreading dynamics of the film, which leads to a complete suppression of the contact line growth above a critical fraction of hydrophilic stripes. Furthermore, we find that increasing the width of the hydrophilic stripes slows down the advancing front, giving smaller critical fractions the wider the hydrophilic stripes are. Using analytical approximations, we quantitatively predict the growth rate of the contact line as a function of the covering fraction, and predict the threshold fraction for saturation as a function of the stripe width.Comment: 11 pages, 5 figure

Quantifying sympathetic neuro-haemodynamic transduction at rest in humans:Insights into sex, ageing and blood pressure control

KEY POINTS: We have developed a simple analytical method for quantifying the transduction of sympathetic activity into vascular tone. This method demonstrates that as women age, the transfer of sympathetic nerve activity into vascular tone is increased, so that for a given level of sympathetic activity there is more vasoconstriction. In men, this measure decreases with age. Test–re‐test analysis demonstrated that the new method is a reliable estimate of sympathetic transduction. We conclude that increased sympathetic vascular coupling contributes to the age‐related increase in blood pressure that occurs in women only. This measure is a reliable estimate of sympathetic transduction in populations with high sympathetic nerve activity. Thus, it will provide information regarding whether treatment targeting the sympathetic nervous system, which interrupts the transfer of sympathetic nerve activity into vascular tone, will be effective in reducing blood pressure in hypertensive patients. This may provide insight into which populations will respond to certain types of anti‐hypertensive medication. ABSTRACT: Sex and age differences in the sympathetic control of resting blood pressure (BP) may be due to differences in the transduction of sympathetic nerve activity (SNA) into vascular tone. Current methods for dynamically quantifying transduction focus on the relationship between SNA and vasoconstriction during a pressor stimulus, which increases BP and may be contra‐indicated in patients. We describe a simple analytical method for quantifying transduction under resting conditions. We performed linear regression analysis of binned muscle SNA burst areas against diastolic BP (DBP). We assessed whether the slope of this relationship reflects the transduction of SNA into DBP. To evaluate this, we investigated whether this measure captures differences in transduction in different populations. Specifically, we (1) quantified transduction in young men (YM), young women (YW), older men (OM) and postmenopausal women (PMW); and (2) measured changes in transduction during β‐blockade using propranolol in YW, YM and PMW. YM had a greater transduction vs. OM (0.10 ± 0.01 mmHg (% s)(−1), n = 23 vs. 0.06 ± 0.01 mmHg (% s)(−1), n = 18; P = 0.003). Transduction was lowest in YW (0.02 ± 0.01 mmHg (% s)(−1), n = 23) and increased during β‐blockade (0.11 ± 0.01 mmHg (% s)(−1); P < 0.001). Transduction in PMW (0.07 ± 0.01 mmHg (% s)(−1), n = 23) was greater compared to YW (P = 0.001), and was not altered during β‐blockade (0.06 ± 0.01 mmHg (% s)(−1); P = 0.98). Importantly, transduction increased in women with age, but decreased in men. Transduction in women intersected that in men at 55 ± 1.5 years. This measure of transduction captures age‐ and sex‐differences in the sympathetic regulation of DBP and may be valuable in quantifying transduction in disease. In particular, this measure may help target treatment strategies in specific hypertensive subpopulations

Dynamics of gravity driven three-dimensional thin films on hydrophilic-hydrophobic patterned substrates

We investigate numerically the dynamics of unstable gravity driven three-dimensional thin liquid films on hydrophilic-hydrophobic patterned substrates of longitudinal stripes and checkerboard arrangements. The thin film can be guided preferentially on hydrophilic longitudinal stripes, while fingers develop on adjacent hydrophobic stripes if their width is large enough. On checkerboard patterns, the film fingering occurs on hydrophobic domains, while lateral spreading is favoured on hydrophilic domains, providing a mechanism to tune the growth rate of the film. By means of kinematical arguments, we quantitatively predict the growth rate of the contact line on checkerboard arrangements, providing a first step towards potential techniques that control thin film growth in experimental setups.Comment: 30 pages, 12 figure